Featured News

  • Saltman Quarterly Article

    Our work understanding and combating the development of Dilated Cardiomyopathy was featured in the Saltman Quarterly. More details and the article can be found here >

Featured Research Article

  • Ankrd1/titin/F-actin binding interface This manuscript describes a new ternary complex at the sarcomeric I-band: Ankrd1/Carp1 binds to titin (N2a) and also forms links to filamentous actin. The article is published in the Journal of Molecular Biology. A great collaborative effort with the labs of Olga Mayans, Wolfgang Linke, Michael Kovermann, Belinda Bullard, Ju Chen and Emma Borgeson.

  • Featured Review Article

    • Cullin-Review article Read our extensive review on the role of cullin-RING ligases for the development and function of cross-striated muscles. The open access article is published here >

About the Lab

We investigate muscle development, signaling and maintenance, by studying the biological role of sarcomeric and muscle associated proteins. We are particularly interested to decipher molecular mechanisms that play a role in the development of cardiac and skeletal muscle myopathies.

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Our laboratory is Green Lab Certified. We aim to do sustainable research to preserve the planets resources.

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News Feed

  • May 2021: Something entirely different from the usual projects in the lab: We looked at challenges to the education of PhD students at universities in Sweden due to COVID-19. The accepted manuscript is now available at BMC Medical Education.
  • Impact of covid on PhD education in Sweden
  • April 2021: We collaborated with the Sheikh Lab at UC San Diego to uncover cardiac functions of the Cop9 Signalosome unit Csn6. The manuscript was recently published at the Journal of Clinical Investigations (JCI).
  • Cardiac Csn6 knockout manuscript
  • April 2021: We have a new collaborative manuscript describing the structure of titin Ig81-83 availabe at the Journal of General Physiology.
  • titin Ig81-83 structure
  • March 2021: Discover our new manuscript that explores obscurin and SPEG kinase biology. The open access article is published here. Another paper with a fantastic team of collaborators- Dr. Fleming at the University of Konstanz and the Borgeson lab at the University of Gothenburg.
  • Exploring obscurin and SPEG kinase biology

    Past news >