Featured News

  • Announcing the 2020 AMC Meeting

    We are working on the next Alternative Muscle Club Meeting, which will be held in late summer or early autumn of 2020 at the UC San Diego Sanford Consortium Building. Join us for a day dedicated to exploring the outstanding work of early career scientists in muscle research.
    More details and deadlines can be found on the AMC2020 Meeting homepage >

Featured Work

  • miR-486 manuscript Our new manuscript published in JCI Insight identifies a novel stretch-responsive cardiac signaling pathway involving the small micro-RNA miR-486. Our work highlights miR-486 changes in hypoplastic left heart syndrome (HLHS) and a sheep model of excessive pulmonary blood flow. Proteome data identified that this miRNA regulates Smad/FoxO1 and Stat1 signaling pathways. The full manuscript can be found here.

About the Lab

We investigate muscle development, signaling and maintenance, by studying the biological role of sarcomeric and muscle associated proteins. We are particularly interested to decipher molecular mechanisms that play a role in the development of cardiac and skeletal muscle myopathies.

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Our laboratory is Green Lab Certified. We aim to do sustainable research to preserve the planets resources.

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